Brazil’s cooperation with African countries has been intensified by South-South agreements in recent years. Within higher education, the cooperation has been mainly focused on the training of professionals for these countries. This paper aims to reflect on the experiences of international cooperation established between Brazil and Africa, especially with Portuguese speaking countries – Guinea Bissau, Angola, Mozambique and Cape Verde. The experiences were developed at the UTFPR Pato Branco campus, in accordance with three agreements. We developed a descriptive study based primarily on official documents and institutional reports. The analysis points to the importance of UTFPR’s effective participation for the institutionalization of higher education in the National School of Administration (ENA) in GuineaBissau, as well as for the training of professionals at undergraduate and graduate levels and for strengthening the science and technology of these African countries.